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Mouad Lamrani

Mouad Lamrani

General Manager of Menicon Co., Ltd R&D, Geneva, France

Title: Free enzyme bio-material as D-glucose sensor

Biography

Biography: Mouad Lamrani

Abstract

Due to diabetes pandemic, a non-invasive technique of blood sugar monitoring is highly needed. Polymers comprising boronic acid (PolyBA) are known as D-glucose sensing materials. Boronic acids bind adjacent cis-diol in D-glucose forming cyclic boronic esters. In the present project, aromatic PolyBAs show a reversible and visible optical change in the presence of D-Glucose at physiological conditions. This optical change is enhanced by co-polymerizing 3-Acrylamidophenylboronic acid (3APB) derivatives and co- monomer called “spacer”. Hydrophilic/hydrophobic fine-tuning composition leads to highly effective sensor system.