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Munawar Hussain

Munawar Hussain

Tuebingen University, Germany

Title: QCM-D as clinical diagnostics tool

Biography

Biography: Munawar Hussain

Abstract

QCM-D (Quartz Crystal Microbalance with Dissipation) has outstanding potential for thrombosis and haemostasis studies in therapeutic directions and decisions.It is also attractive as diagnostic tool for clinical challenges in the prospective of cost-effectiveness, robustness and straightforwardness. An important relevant example is Heparin induced thrombocytopenia (HIT) platelet aggregation diagnostics. For HIT today’s clinics rely on functional assays including HIPA tests (heparin induced platelet aggregation) and serotonin release tests. These tests are tedious, time consuming and costly. HIT assays are part of clinical diagnostic but these need high expertise in this area. Owing to tediousness, time consumption and costs such tests should not be performed in laboratories with limited experiences in this area. QCM-D has outstanding potential for HIT detection of destructive antibodies via using ultrasensitive thin films.