Professor, Director, Western’s Industry 4.0 Network, Western University, Canada
Title: From Lab-on-a-chip to Lab-on-a-tip for Point-of-care Diagnostics of whole blood samples
Biography: Jun Yang
Point-of-care (POC) testing offers rapid results of diagnostics near the site of patient care, which can significantly improve health care and management of infectious diseases. Blood tests are the most commonly-used diagnostic methods nowadays because blood analyses provide definitive information of medical conditions of patients. Traditional blood tests are conducted using large-scale blood analyzers, which are equipped in centralized laboratories and only operated by highly trained personnel. The traditional blood tests are time and cost consuming, and labor extensive. With the development of Lab-on-a-chip technology, biochemical experiments can be performed automatically on single chips. However on-chip blood testing is challenging because the whole blood is a complex non-Newtonian fluid with high constituent of blood cells. Here I will present our recent developments of Lab-on-a-chip and Lab-on-a-tip technologies, i.e. integrating chemical biosensors into Lab-on-a-CD devices and integrating surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) on optical fibers, for POC diagnostics of whole blood samples.