Biochips & Nucleic Acid Sensors

A hypothetical computer logic circuit or storage device in which the physical or chemical properties of large biological molecules (as proteins) are used to process information. A Biochip is a combination of minute DNA spots hooked up to a hard surface. Scientists use DNA Biochips to check the expression levels of huge number of genes at the same time. Each DNA spot contains Pico moles of a précised DNA sequence known as a probe. These can be tiny section of a gene or a DNA particle that are used to cross breed a DNA or RNA. Immunosensors are built by means of the appropriate combination of the biomolecules with the transducers used together; they can be applied in specific analytical situations. Immunosensors commonly rely on the reuse of the same receptor surface for many measurements. Aptamers are oligonucleotide or peptide molecules that bind to a specific target molecule. Aptamers are usually created by selecting them from a large random sequence pool, but natural aptamers also exist in riboswitches.

  • DNA chips
  • Aptasensors
  • Immunosensors
  • Organism and whole cell-based biosensors
  • Aptamers and their biological applications
  • Natural & synthetic receptors (including molecularly imprinted polymers)
  • Microarray

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