Xiaohao Wang
Tsinghua-Berkeley Shenzhen Institute, China
Title: Microfluidic chip ionization source coupling with mass spectrometry
Biography
Biography: Xiaohao Wang
Abstract
Ionization source is a vital component of the mass spectrometer. In recent years, with the development of the mass spectrometer miniaturization and the microfluidic chip integration technologies, increasing research efforts have been devoted to the coupling of microfluidic chip ionization source to mass spectrometry. Facing requirement of portable MS used for on-site rapid detection, a microfluidic chip ionization source is developed. Multi-layer soft photolithography technology is chosen as the fabrication craft for the microfluidic chip template, and three novel microfluidic chip ionization sources were proposed, such as a microfluidic chip-based multi-channel ionization (MCMCI) was developed to extend the application of microfluidic chip ionization to MS. This MCMCI implemented extraction of untreated compounds in complex matrices without sample pretreatments and dual sprays with high DC voltages simultaneously.